Cross-presentation: how to get there – or how to get the ER

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Cross-Presentation: How to Get there – or How to Get the ER

Antigen cross-presentation enables dendritic cells (DCs) to present extracellular antigens on major histocompatibility complex (MHC) I molecules, a process that plays an important role in the induction of immune responses against viruses and tumors and in the induction of peripheral tolerance. In order to allow intracellular processing for cross-presentation, internalized antigens are targeted ...

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ژورنال

عنوان ژورنال: Frontiers in Immunology

سال: 2012

ISSN: 1664-3224

DOI: 10.3389/fimmu.2011.00087